Jared Padalecki portrayed Dean in Gilmore Girls and then, in Supernatural, his chararacter Sam had a brother named Dean.
Jared Padalecki's roles in Gilmore Girls and Supernatural are among his most well known:
[He] rose to fame in the early 2000s after appearing [as Dean Forester] on the television series Gilmore Girls [...]. Padalecki is best known for his role as Sam Winchester on Supernatural.
Has anyone involved in making Supernatural ever mentioned whether Sam's brother being named Dean was a reference to Gilmore Girls?