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In the animated film Halo: The Fall of Reach, "Fletcher's Syndrome" is mentioned as a potential side-effect of the augmentation process.

Is there any source or material that says what this syndrome is, and what the effects of having it are? It doesn't sound pleasant.

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    Well, first you get a cardboard tube and a gerbil... – Broklynite Mar 22 '16 at 21:10
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    @Broklynite - No, that's Gere Syndrome. – Valorum Mar 22 '16 at 22:09
  • @Richard this guy gets it at least – Broklynite Mar 22 '16 at 22:25
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    Given that there is no real "Fletcher's Syndrome", my guess is that a treatment that is supposed to result in "Alteration of bioeletrical nerve transduction to shielded electronic transduction. 300% increase in subject reflexes" is likely to lead to substantial neurological malfunction, ataxia, impairment and mental degradation. – Valorum Mar 22 '16 at 22:52
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If you look through all the lore and the equivalence to real life, Fletcher Syndrome is a systemic failure of vitals in a long lasting and painful manner.

Symptoms: Cranial Hemorrhaging, Cardiac Hemorrhaging, Spasms in disconnected tissue, Complete Muscle Collapse, Sensory Deprivation, Digestive Tract Bloating, Malnutrition, and the lowering of the immune system.

There is no cure and presumably wouldn't have any due to the lack of ability to address so many situations at once.

Multiple organ dysfunction syndrome (MODS) is the less extreme, yet real life version of Fletcher Syndrome. Though it doesn't contain all of the symptoms, it does contain the most crucial symptoms of Total Organ Failure.

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