I was revisiting this question and found @Valorum's comment interesting.
That's covered in the excellent (and fully canon) Star Trek: The Next Generation Technical Manual. I quote; "These units are primarily designed for operation at molecular (non-lifeform) resolution for cargo use, but can be set to quantum (lifeform) resolution if desired, although such usage would entail a signification reduction in payload mass capacity". For the record, the cargo Tranporter on the original Enterprise is rated to carry 22 crewmembers (1.6 metric tonnes?) in an emergency. – Valorum
It makes me wonder if inanimate cargo transported at molecular resolution degrades during the relocation process. What does canon say?
Is inanimate mass transported between point A and point B in some way lesser than it was prior to beaming? If not, then why do they need a Quantum Resolution setting to beam lifeforms?