No, it's not unique.
HANDBOT: Statement rejected. Apalapucia is under planet-wide quarantine. This is a kindness facility for those infected with Chen Seven.
(The Doctor covers his mouth and nose with his coat lapel.)
DOCTOR: What?
RORY: Chen Seven, hmm?
DOCTOR: The one day plague.
RORY: What, you get it for a day?
DOCTOR: No, you get it, and you die in a day.
HANDBOT: There are forty thousand residents in the Twostreams Facility. Please remain in the sterile areas. Visiting hours are now.
(The Handbot beams itself away.)
DOCTOR: Sterile area. I'm safe.
AMY: What about me?
DOCTOR: Chen Seven only affects two-hearted races like Apalapucians.
So at least the Apalapucians have two hearts as well. And based on the same episode, they are humanoids too. So there has probably been other reasons how he recognised Missy as Time Lord. For example Time Lords telephatic ability to sense other Time Lords. (Seen at least in The End of Time parts 1 & 2 and in The Doctor's Wife)