Could one read Alan Moore's four-issue series Neonomicon before reading the two-issue series The Courtyard?
If the plot is already set in The Courtyard, is the reader going to understand anything in the Neonomicon?
The narrative of Neonomicon is independent of the Courtyard, and makes sense without it. However, you will miss important character details. You'll be able to glean what you need from context, but there's really no reason to not just read The Courtyard first and get the full experience.