We know that Melange is addictive and it's not a mere psychological addiction like in the case of Nicotine; where if you don't smoke it you feel nervous and generally unwell but you won't get seriously sick if going "cold turkey", but it permanently changes your physiology, which means that withdrawal could kill you.
But how long does one have to be exposed to Spice to get addicted to the point of no return? One spiced cake? Few months of regular eating that also turns your eyes blue? And following that, is there a way to break the substance dependency?
The linked question explains the addictive dose but not how often and for how long one would have to use it to create the dependency. For example I could smoke two packets of cigarettes in one day and only get sick, not addicted; smoking few every day (from the same packages) in a period of few weeks would be a serious risk of addiction.