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Reminds me of a giant version of the alien that took over Superman in Batman Beyond JLU episode, but I don't think they are the same.
Is it a classic dc comics villain?
Looks suspiciously like Starro the Conqueror, from the first appearance of the Justice League as a team in The Brave and the Bold #28 (1960).
His Wikipedia article also lists his appearance in The Powerless, and so does ScreenRant.
Required, but never shown