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I remember fighting and shooting everything as Duke spouted one liners he borrowed from Bruce Campbell. What prevented the dancing girls & Duke Nukem from morphing during crisises that made him our last, crass hope for mankind?
Duke Nukem 3D

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    If anything was needed to prevent mutation, I'd say it was an excess of testosterone and all-around awesomeness. – Omegacron Dec 30 '14 at 19:51
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    @Valorum Wait. WHAT? The other question is a dup of mine. – Major Stackings Jun 16 '16 at 19:18
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    @MajorStackings - My answer to the other question answers this one. Duke = Too badass to mutate. – Valorum Jun 16 '16 at 19:30
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    @Valorum you answered the dupe shame on you :P. this one was asked 1 year earlier – Himarm Jun 16 '16 at 19:31
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    @Valorum Well, oops. You did that bass ackwards. – Major Stackings Jun 16 '16 at 20:07
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In Duke Nukem Forever, there is no mutation. The Aliens bring their pigs with them. In Duke Nukem: Manhattan Project there was this green mutation goo, that reduced your health. I'd say you need long exposure (especially being a big tough guy like the Duke) to the goo in order to mutate. As for "the chicks", we learn in Forever that the aliens require live women to breed their offspring, so it wouldn't make sense to mutate them.

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I asked the co-creator of Duke Nukem; George Broussard this question on twitter.

His response is simply that Duke is too badass to mutate.

Q : "I'm struggling to work out why Duke isn't mutated by his own GLOPP gun. Any ideas?"

A : "You can't mutate [a] bad motherf*cker.

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