To add on to the previous answers, the homecoming dance is a major plot point in the film:
At that critical scene, he makes the decision between his love interest, Liz, and stopping Vulture from his criminal activities.
But it's worse than that, because
Vulture, not to be clichéd or anything, turns out to be Liz's father. (To break the cliché, though, Liz doesn't know of either her father's or Peter's alter egos.) It's because of that homecoming dance that Vulture finds out who Spiderman really is.
I'm sure someone out there is still trying to connect homecoming to the Winter Soldier command words:
Longing, Rusted, Seventeen, Daybreak, Furnace, Nine, Benign, Homecoming, One, Freight Car. Good morning, Soldier.