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In Spider Man Reign, Peter Parker passes radioactive semen into Mary Jane, which caused Mary Jane to get cancer and die. To my mind, this qualifies as a sexually transmitted disease.

"Oh God, I’m sorry! The doctors didn’t understand how it happened! How you had been poisoned by radioactivity! How your body slowly became riddled with cancer! I did. I was… I am filled with radioactive blood. And not just blood. Every fluid. Touching me… loving me… Loving me killed you!"

Are there any other Marvel characters that have been shown to have sexually transmitted infections?

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    There's a handful of moderately prominent DC characters with AIDS and HIV (including a couple of the current lineup of the Teen Titans). A cursory search reveals no Marvel superheroes, only minor non-powered characters.
    – Valorum
    Aug 4, 2017 at 7:55
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    Difference between STI and STD would be applicable here stdcheck.com/blog/std-vs-sti-whats-the-difference
    – user001
    Aug 4, 2017 at 8:38
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    @ths that's what you find hard to believe, and not how it gave him superpowers?
    – OrangeDog
    Aug 4, 2017 at 9:31
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    "To my mind, this qualifies as a sexually transmitted disease." No, it doesn't. The cancer was caused by radiation, not directly transmitted via sex. You're stretching the definition way beyond breaking point here.
    – Anthony Grist
    Aug 4, 2017 at 10:32
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    @AnthonyGrist to be fair... so it the comic.
    – KutuluMike
    Aug 4, 2017 at 12:26

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James Wilson is said to have HIV/AIDS. Marvel Comics

Incredible Hulk #388. In this story it is stated that Jim Wilson was suffering from HIV/AIDS

There are a bunch more on this site but from different comic studios. https://www.stdcheck.com/blog/comic-book-superheroes-hiv-immune-stds/

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