• Let us assume that the events in Game of Thrones end with the two Dragons surviving without any major harm being done to them.

  • Dragons are known to be able to change their gender, so let us assume that we end up with a breeding pair of Dragons.

Even if these two Dragons are not related (and I believe they are), is the two of them sufficient to breed a new race of Dragons? Or will they suffer the genetic issues from in-breeding?

Assuming that Dragons have a similar genetic deposition to lizards, do lizards typically suffer with the genetic issues from in-breeding? Is this a work around?

Are there any other known Dragon eggs in the world of Game of Thrones? Could this be a way for our two Dragons to find the genetic diversity necessary to ensure the continuation of their species?

If there are only two Dragons left to procreate, and they are prone to to the issues of in-breeding, is the future of the Dragon species doomed?

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    Unfortunately, we don't have the knowledge we need to answer this question, it is therefore opinion based. – Edlothiad Sep 7 '17 at 16:05
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    Targaryens purposefully inbreed for better dragon riding genes. I think inbreeding works slightly differently in GoT. – TheLethalCarrot Sep 7 '17 at 16:06
  • Related/possible dupe: scifi.stackexchange.com/questions/169037/… – Skooba Sep 7 '17 at 16:46
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    I would have liked to write this as an answer... Assuming a similar genetic disposition like for example lizards, a minimum population of 15 is required in order to have a propability to survive 10 or more generations. With a lower population and seen from point Biology the 10th generation will suffer of the inbred effects. Considering the possibility to change their gender, the population could be reduced to 8. The answer can also be found at another stack-exchange. --> worldbuilding.stackexchange.com/questions/3/… – Calypticus Sep 8 '17 at 9:18