I believe she did in the movie, but I'm not sure about in the book.
The only example of Deletrius being cast that we see is when Amos Diggory uses it to make the ghost of a spell created by Prior Incantato disappear:
'Prior Incantato!' roared Mr Diggory.
Harry heard Hermione gasp, horrified, as a gigantic serpent-tongued skull erupted from the point where the two wands met, but it was a mere shadow of the green skull high above them, it looked as though it was made of thick grey smoke: the ghost of a spell.
'Deletrius!' Mr Diggory shouted, and the smoky skull vanished in a wisp of smoke.
Harry Potter and the Goblet of Fire - pp.121-2 - Bloomsbury - Chapter 9, The Dark Mark
There is no canon indication that this is a generally destructive spell, or suitable for use in combat, or anything other than Prior Incantato's "stop button".
The example of Deletrius being used in The Goblet of Fire bears no resemblance to Bellatrix's death in the book.
Molly's curse soared beneath Bellatrix's outstretched arm and hit her squarely in the chest, directly over her heart.
Bellatrix's gloating smile froze, her eyes seemed to bulge: for the tiniest space of time she knew what had happened, and then she toppled, and the watching crowd roared, and Voldemort screamed.
Harry Potter and the Deathly Hallows - p.590 - Bloomsbury - Chapter 36, The Flaw in the Plan