I recently came across some Thanos fan-art depicting the mad-Titan as a female (image below). This got me thinking, is there an alternate version of Thanos who is female?
The linked Marvel page describes Thanos bringing her into existence as follows.
When Death turned her back on Thanos while he was in possession of the Infinity Gauntlet, Thanos created a new partner and equal who he named Terraxia. He created Terraxia in his likeness but still left her with some frailties.
She was shown to be created by Thanos in Infinity Gauntlet #3.
She is later killed in Infinity Gauntlet #5 by Nebula.
She briefly shows up in What If...? #49 but only for the Silver Surfer to put her back into none existence.
Lastly, although I figure you may already know this the image you link is from Deviant Art user "NeoArtCorE" and a fan art suggesting Thanos has used the Infinity Gauntlet for gender changes.
Fanart : Thanos from Avengers: Infinity War
No spoilers thread!! Infinity Gauntlet, Infinity Power for gender changes