I remember reading an issue of a Vault of Horror/Tales From The Crypt type comic in the late 70s/the early 80s, and one story stuck with me and I am trying to track it down.
The story centers around a honeymooning couple who are on an ocean cruise liner. Everything is going fine until the crew of the ship pick up a survivor in a lifeboat. This survivor is infected with some kind of virus/disease which is spread by contact with another person and compels the infected individual to pass it on to any uninfected in proximity (similar to the Crossed virus, or the Rage virus). It also mutates the infected to a (slightly) larger size and makes them ugly (oversized forehead, deep set eyes, like the Hulk, or Ben Grimm).
The newlyweds manage to barricade themselves in their cabin until they are the only ones uninfected, but as the infected try to break in, they decide to climb out of the window and take their chances in the sea. The husband manages to climb outside, but as his wife is climbing through the window the infected break in and someone grabs her ankle, passing the virus to her, and the husband is forced to abandon her.
Does this ring a bell with anyone?