Pokemon are known to be able to withstand tremendous physical abuse before being KOed (death happens very rarely, if at all): being burned, shocked with millions of volts, subjected to Light That Burns the Sky itself, etc etc.
What about humans, though? They seem to be far more fragile than Pokemon, since they usually aren't seen fighting Pokemon and they are explicitely said to need Pokemon for protection. Noticeably, in one of the very early Anime episodes, Ash managed to "catch" a wild (presumably very low-level) Pidgey with his coat but failed to hold it - hinting that humans seem to be weaker than the weakest of Pokemon.
However, we also have examples that seem to contradict this. Jessie and James, noticeably, were able to survive being launched into orbit and falling back on Earth. Also, in one anime episode, Kiyo was able to defeat a Tyroque even though both his pokemon had failed at this task. So it would seem human bodies do possess powers comparable to those of Pokemon after all.
Is this settled in universe? How powerful are (unarmed) humans in the world of Pokemon?