If the Borg were to attack the planet Vulcan, could Vulcans incapacitate Borg drones using the Vulcan nerve pinch?
A nerve pinch would (with reasonable certainty) work on a humanoid Borg.
Tuvok is just about to "attempt" it in VOY: Unimatrix Zero, Part II when he's interrupted. Given that he's the ship's Security Officer and has extensive hands-on knowledge of Borg physiology, it seems very unlikely that he'd try it if he wasn't reasonably confident that it'll work.
TUVOK: I will attempt to deactivate him.
And we see Spock doing it (successfully) in the Star Trek comic Boldly Go #4
For the record, it doesn't work at all in the non-canon Star Trek Online game, showing effectiveness only on (some) entirely biological organisms.