The villain in question was notable for having a supply of chemicals on his costume. I seem to recall several large test tubes in several rows on the chest of his costume. I think it was six tubes in three rows, with the bottles on each side feeding into a tube apparatus.
The villain used those chemicals to create superpower like effects. I seem to recall him mixing up something to make a super-cold effect or the like. I cannot recall the full range of what he could create (and I'm certain it was a male villain), but the other powers were probably along those line (flame, gas, etc.)
I cannot remember who the villain was fighting, or if it was mid-to-late 60's-era or the 70's. I'm almost certain it was no later than the 1970s. I don't recall if the villain was a "one-off", but I'm fairly certain this was a minor villain that wasn't a recurring nemesis for any superhero.
As I mentioned before, 60's to 70's, probably not the latter 1970s if at all.