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In the film version of Harry Potter and the Goblet of Fire we see Moody with a pocket watch that he uses several times.
Click image to enlarge.
It has a bio-hazard like symbol with an eye in the middle and a sort of shading in the background? What is this?
There are also runes around the outside but I'd imagine these are just numbers considering their placement.
An eye in the middle of a symbol is in almost cases referred by as "all seeing eye". This is a symbol of early Christian, to show the eye of God, watching over humanity (Wikipedia "Eye of Providence")
If I assume the background are three moons with points of intersection (see the picture), then this three are the symbol of "Triple Crescent Moon". Like this website wrote: a symbol for three stages of women life, or in general three fates (birth, life and death). And it should be the opposite to the horned god.
Strange thing: If one search for pictures with "symbol triple crescent moons" one gets some of biohazard as jewelry too...
Like I wrote in my comment: The three outer circles in biohazard symbol do touch, but have no point of intersection. The symbol on Moody's clock clearly have outer circles with point of intersection.
So it is not the biohazard symbol, but the similarity is intended I assume, to illustrate the role of Moody as an Auror, who watch over the "normal" people (magic and non magic) to find the evil and guard them against it. "Magic-hazard", if you want to call it that.
This symbols appears on a pocket watch, and pocket watches were traditionally personalized items. They were traditional signs of status, and even simple ones were often engraved with the owner's monogram on the case. British lords could have them further customized with their family crests or escutcheons on the case or the dial.
Based on these real-world background facts, I assumed that the symbol was Mad-Eye Moody's personal emblem. It is thematically appropriate, with an eye appearing in a (close approximation of a) biohazard symbol—metaphorically indicating that his "mad" eye is dangerous on its own. It is also vaguely suggestive of the masonic eye emblems that masonic lodge members sometimes incorporated into their personal crests.
It's a reference to Mad-Eye Moody's actor Brendan Gleeson's role as Frank in 28 Days Later, a popular zombie flick from 2002. In addition, it features Norse runes for the 1, 2, 4, 5, 7, 8, 10, and 11.
