It's not Frank Herbert's Hellstrom's Hive.
Cannot find old 20+ years paperback scifi novel about insect-human hive in Siberia. A man follows his brother to work in a research station in Siberia. His brother looks after the (sledge?) dogs in the secret facility. The hive is destroyed and man leaves on a plane together with (daughter?) of the scientist who bred the hybrids. The plane crashes and we do not find out what happens to author.