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In Marvel's What If..? episode 3 we see that

Hank Pym, as Yellowjacket, is on a revenge mission against S.H.I.E.L.D. because Hope has died. Hank is murdering the future Avengers one by one, and even manages to make the Hulk explode by entering his bloodstream and shooting a resizer disk into his heart. Doesn't this prove the Ant-Man-entering-Thanos'-rectum theory plausible, meaning that in the main Marvel Cinematic Universe, future enemies could be defeated by Scott Lang employing similar tactics?

Are there any comic examples of Ant-Man entering an enemy's body in order to defeat them? And if so, has any villain ever prevented this in some way?

I found a comic cover where he is inside a bloodstream. Though I don't know why, he definitely has been inside someone before.

Ant-Man 2015 #5 Ant-Man 2015 #5 cover art

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  • There's no indication Scott ever became Ant-Man in that universe. In fact, given what we saw happen, he probably didn't. We don't even know if this universe will feature again at the moment. I'm not really sure what your question is either to be honest.
    – TheLethalCarrot
    Commented Aug 27, 2021 at 13:00
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    Could but would he think of it? Also killing people like that isn't exactly the sort of things heroes do.
    – TheLethalCarrot
    Commented Aug 27, 2021 at 13:04
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    Not necessarily. A lot of it depends on whether or not he can expand himself enough to "throw" a disc and get out. In Bruce's case, he was basically able to get to empty space and expand before throwing the disk, shrinking down, and leaving. The rules for when Ant-Man can expand aren't entirely fleshed out. For all we know, it might have squished him to try expanding somewhere other than inside a regular human's chest cavity.
    – FuzzyBoots
    Commented Aug 27, 2021 at 14:25
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    Note that Loki fully blanks the same attack in said episode
    – Rogue Jedi
    Commented Aug 27, 2021 at 15:46
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    "if a villian is going to kill his daughter who wouldn't kill that person?" — As Dumbledore said in Lord of the Rings, "We don't trade lives". Commented Aug 27, 2021 at 16:00

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Hank Pym (as Hank Pym the Scientific Adventurer) once shrank Wonder Man down so that he could go inside a (fake) Ultron and then return to normal size, destroying the Ultron. This was in an issue of West Coast Avengers back in the 1990s.

West Coast Avengers #42, Issue Date: March 1989, 'One of our Androids is Missing!'

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    West Coast Avengers #42, Issue Date: March 1989, 'One of our Androids is Missing!' Commented Sep 12, 2021 at 12:32

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