I've just rewatched Blade (1998), and I'm trying to figure out which city this movie is set in, which it never clearly states. It has been some time since I listened to the director's commentary, and I do not remember any mention of that.
Here are the clues I could find:
Probably somewhere in the contiguous United States, in a city with skyscrapers, and a subway.
The movie was shot in Los Angeles, but that doesn't necessary mean it takes place in Los Angeles. In lots of other productions scenes can be shot in one city, but diegetically take place somewhere else. Even the last minute of Blade itself takes place in Moscow, and I am pretty sure they did not go to Moscow for that one scene.
Currently Wikipedia also says "begins in a Los Angeles nightclub", but I doubt they have a good source for that location.
In the very beginning we see Vanessa Brooks' Drivers'License, which says Braxton, FL 90032. Although this could mean that the intro takes place in Braxton, Florida, or she just got her licence there, and does not mean the bulk of the movie takes place there, especially as Blade & Whistler mention that they move around a lot.
There is apparently a Map of New Orleans visible at some point, but I doubt it means this is supposed to take place in New Orleans, as then there should be some further visual hints of the environments. Interview with the Vampire, e.g., made sure to show the unique details of that city. The map could also be a generic map prop, and not necesarily show the actual city.
When Frost kills the vampire elder with a sunrise he goes to the coast (of the ocean, presumably, or a giant lake), and they watch the sunrise. Which it should from the East, which means their city should have the ocean or a great lake to the east of it. Although this could also probably be an overlooked detail.
Then there is the vampire-temple, which might indicate that at some point in the past there was a major population centre in that spot, although this is a very fuzzy argument.
I always felt the city was supposed to be Detroit, with its large decrepit factories, and with Blade's muscle-car being maybe a nod to it, although this is probably just conjecture on my part.
The only detail I am sure of is that Officer Krieger (the vampire familiar cop) has a patch that says Center City Police. I think this is supposed to be a fictional city, similar to how Metropolis or Gotham are fictional settings for movies. But I cannot find any other reference to that in the movie, or through a quick websearch.
Does anybody have any definitive source? Or am I just really overthinking this? :P