I have been looking for this live action show for well over 10 years now, I think. I saw a few episodes somewhere between 2008-2010 but the show may have been a few years older. I watched it on Sci-Fi. The description sounds vague at first but by the end you will know what I'm talking about if you know the show.
It takes place in a futuristic world. I don't think it was Earth as I remember characters from multiple invented planets. I don't recall any makeup or heavy prosthetics. Everyone looked human.
I believe the plot begins with us seeing a teen girl in a video game that is similar to the metaverse. She's at a party or concert, I think, looking for a friend that I believe she eventually finds and briefly speaks with before being called downstairs by her mother in real life and signing off. Shortly after, she gets into a fight with her mom. She says something nasty and her mom slaps her so she angrily leaves. Her mother believed she was going to school but it becomes apparent to the viewer that she actually intends to run away.
We later see the girl on a train sending her mom a message saying something like "don't live in regret, I forgive you" and before it completely sends, a bomb goes off on the train.
Eventually the police think that the girl had something to do with the attack because of the cryptic message she sent her mother.
A bunch of other stuff happens but it was so long ago, the other memories aren't strong enough to describe.