In the Chronicles of Pern series, the people of Pern were threatened for centuries by periodic attacks from Thread, a devastating alien organism that consumed all organic material. The dragonriders were able to combat Thread by searing it midair with their dragons' fiery breath. However, records show that early in the colonization of Pern, before the dragons were genetically engineered, the settlers were unable to stop the predations of Thread.
What abilities, resources, or knowledge did the original colonists lack that prevented them from effectively fighting Thread? Was it simply the lack of flying dragons, or were there other factors involved? Surely with all their high technology, ingenuity and will to survive, the settlers must have attempted some means to counter the Thread attacks using the resources available to them at that time. What held them back until the dragons came?