Jack Harrison (Jeff Goldblum) and Gil Turner (Ed Begley Jr.) are
writers for The Sensation, a supermarket-grade tabloid run by Turner's
father, Mac Turner (Norman Fell). Jack is a more serious journalist,
using The Sensation as a stepping stone to a better career and aspires
to work for Time magazine, while Gil is a gangling yes-man, ever ready
to win his father's approval.
When Mac receives a homemade videotape of two panicked men running
from a creature they believe to be Frankenstein's monster, along with
a waist-down shot of the suspected monster, he dispatches his son and
Jack to Transylvania to follow the lead. Jack tries unsuccessfully to
beg off, but is told by Mac that if they both again come back with
nothing, they are both fired. They have to bring a story that will
bring a banner headline "Frankenstein Lives!"
Planes, trains and buses later, Jack and Gil arrive at their
destination. Once off the bus, Jack immediately spots Elizabeth
Ellison, a pretty female tourist (Teresa Ganzel) from New York City,
whom he propositions. Gil immediately sets out on their assignment,
just as quickly drawing hysterical ridicule when he tries to question
a hotel desk clerk about the whereabouts of Frankenstein, who shares
Gil's inquiries with the staff and patrons, including the mayor
Lepescu (Jeffrey Jones).
Jack rescues Gil and pulls him out of the hotel to avoid further
embarrassment. Both then take off for their hotel. Seeing them leave,
a gypsy woman named Madame Morovia (Inge Appelt) orders her male
companion to bring them to her.
Jack and Gil arrive at their hotel, which resembles a 17th-century
castle, complete with a gated entrance, but adorned with an "Opening
Soon!" banner and signs denoting the acceptance of credit cards. They
are met at the gate by Fejos (Michael Richards), a butler with an odd
sense of humor. They meet for brunch with Lepescu, where they also
meet Radu (John Byner), his hunched-over manservant who addresses
everyone as "master" and his wife Lupi (Carol Kane).
Both Gil and Jack learn that something is amiss about Transylvania,
despite being laughed off by the locals, including Inspector Percek
(Božidar Smiljanić), head of the local police. After meeting Morovia,
who tells them they must continue their pursuit, they encounter a
series of real-life horror creatures, including a Wolfman Larry
(Donald Gibb), a nymphomaniac vampire Odette (Geena Davis), and a
swamp monster Twisto that grabs Gil by the crotch as he tries to
escape a frightening face-to-face confrontation with the object of
their mission himself.
They eventually learn of a Sicilian doctor, Victorio Malavaqua (Joseph
Bologna), who lost his license to practice medicine. Finding out that
Malavaqua has been giving care in a sanitorium, Gil tries to go there
to make an appointment but is rebuffed by the guard. Gil eventually
sneaks in and finds Percek and Malavaqua talking about the latter's
"experiments", including one involving a patient, Kurt Hunyadi, that
fits the description of the Frankenstein monster, which Malavaqua
claimed had died. An exhumation of the body later proves otherwise.
Gil learns that Radu is in cahoots with Malavaqua, serving as his lab
assistant. Malavaqua also displays a tendency towards madness when
within the confines of his laboratory, but returns to normal when he
leaves it. It is later revealed, as Gil and Jack go on a search for
Elizabeth's missing daughter Laura, that not only has Malavaqua faked
Hunyadi's death, but is also his creator, along with that of Odette,
Larry, and Twisto. It is also revealed that Malavaqua has engaged in
this type of bizarre work to clear his family's name.
The story ties together after Jack is attacked by the Wolfman. In an
attempt to rescue Jack, Gil pulls him off Jack, only to be carted off
by the Wolfman. The police arrive, but refuse to listen to Jack's
story and order him put in the local police lockup. Elizabeth rescues
him and learns that the entire police force is at the wine festival
instead of searching for her missing daughter. Jack heads off to
Malavaqua's lab and Elizabeth goes to the festival. As she is being
hauled away by police after confronting Percek, the town is horrified
as the monster returns in the flesh, carrying Laura in his arms.
Perceived to be dead, it is later learned she was just sleeping.
Jack and Gil arrive, having confronted Malavaqua, and explain
Malavaqua's actions to the townspeople, that Malavaqua was
legitimately trying to create normal lives for those seen as outcasts
or freaks by the townspeople, who now welcome them with open arms.
Finding out that the story is even bigger than what they bargained
for, Gil takes enough pictures and both gather enough material to last
weeks for the tabloid. They more than make up for their failures and
Mac gets his banner headline.