I read this novel at least forty years ago but I think it is even much, much older.
The theme is the existence of a huge toxic cloud in outer space, and at some point Earth trajectory goes through it.
The toxicity of the cloud has a horrific effect on people, it makes them go crazy.
I don't remember much. One detail I do remember is that scientists who follow the evolution of the epidemics of madness note that it is much worse in Africa, for instance, than in Europe. Their explanation of this fact is not at all "politically correct". Of course, one would not expect political correctness in a book which was written so long ago, and which reflects the prejudices of that time.