The Doctor : There is fixed points in time.
So, we can ask ourselves how The Doctor knows which point is fixed and which is not.
While she was looking into the heart of the Tardis, Rose saw what the Doctor sees, so she was as aware of this fact as him.
Think about what could happened if Rose saved herself to disappearing from this universe: the Doctor would surely stay with her as long as possible. So he would probably not meet his other companions, especially not Amy.
No Amy to... have fun in the Tardis, no River. No River, no Doctor, 'cause he would probably died in "The name of the Doctor", killed at the door of his tomb.
So, in my mind, Rose was aware that she was going to disappear. But she has also conscious that she can't do anything against it without destroying the Universe.