I remember a particular story in a comic in the UK (could have been a US import though), it regards a couple on a honeymoon cruise on a liner.
The ship picks up someone in a lifeboat (or directly from the sea?), but it turns out that this person has some sort of disease that turns the victim into an overgrown monster (bit hulk-like).
The disease is passed on by touch, and spreads through the ship like wildfire. The newly-weds are soon the only ones left, and as they prepare to jump overboard, the wife gets infected and the husband must escape alone.
Any ideas? Bit vague I know! Thanks, Chris