I am looking for interesting books or short stories that try to give a reasonable explanation for the existence of talking, gun-shooting, vehicle-driving animals. Something like uplift, or convergent evolution, or selective breeding. If not, a simple, fun, action-packed adventure would do.
The graphic novel WE3 by writer Grant Morrison and artist Frank Quitely is pretty interesting and plausible and rather close to what you are asking.
The story follows the journey of We3, a squad of three prototype "animal weapons," as they flee captivity. The group consists of a dog, "Bandit" a.k.a. "1"; a cat, "Tinker" a.k.a. "2"; and a rabbit, "Pirate" a.k.a. "3", who were all kidnapped from a nearby city and encased in robotic armor. They were also given a limited ability to speak through skull implants. Their body armor fields numerous weapons, including mine laying devices, machine guns and razor claws.
As personal opinion goes, I loved it. It feels real and terrible and sad and works as a commentary on control and abuse of power. Highly recommended.
The GN consists of a three-issue miniseries, and all three covers were great, but cover number one really got to me. The right combination of illustration and photo-realism that is hard to achieve: