In "Conspiracy," an enhanced Admiral Quinn mops the floor with both Riker and Worf, and chucks Geordi through the quarters' automatic doors. Could Data have incapacitated Quinn as easily as Worf taking out Picard, or would the altered admiral have some sort of a chance?
Data is extremely strong, consider this exchange from his trial in the episode "The Measure of a Man":
RIKER: Your Honour, I offer in evidence prosecution's exhibit A, a rod of par-steel. Tensile strength, forty kilobars. Commander, would you bend that?
PICARD: Objection. There are many life forms possessed of mega strength. These issues are not relevant to this hearing.
PHILLIPA: I'm afraid I can't agree, Captain. Proceed with you demonstration, Commander.
(Data bends the heavy rod neatly into a U shape)
Tensile strength is measured in force per unit area, usually in terms of megapascals; this page mentions that 1 bar = 0.1 megapascals, so 40 kilobars = 40000 bars = 4000 megapascals, significantly stronger than any type of steel listed in the table in the tensile strength article (edit: Dan Neely points out there is one I missed with a strength over 5000 megapascals), and about as strong as Kevlar which is used in bulletproof vests. Assuming Quinn's strength was just due to things like adrenaline rather than the parasites radically reengineering his whole body including the composition of bones and muscles (and there was no suggestion of such a thing in the episode), there's no way he could have been nearly that strong. And Data is also able to move much faster than a human, as shown in the episode "The Naked Now" when he had to replace the isolinear chips in engineering in order to allow the ship to escape an exploding star. So yes, I think Data could have easily defeated him in physical combat.
Yes, Data would mop the floor with an adrenalin/endorphin enhanced Quinn. The adrenalin/endorphin enhanced Quinn can manhandle a normal human or Klingon, but Data is orders of magnitude stronger that either race. He possesses mega-strength and has a very durable structure, Whereas Quinn is only a man and fragile by comparison.
The only thing that would make it even close is Data's programming to do the least amount of harm as possible. If Data went full out and got medieval on him it would be over in a second or two, with Data the victor.