I read the GOT books long before I started watching the show. Most things hold up but I don't think that the women are getting enough credit in the show for what they did in the books. For example
All throughout the book series Cersei has used her Gods given power of manipulation, she used blackmail, sex and poison to get what she wanted out of people in the books. When Tyrion was in prison after his trial by combat for the Joffrey thing, Jaime came to set him free and Tyrion said something like 'Man, she's been sleeping around...a lot' (paraphrasing), and she didn't even do that in the show. Lancel Lannister was the only one and it wasn't even a big deal, and it was her cousin (yeah but it was her first cousin).
Why when they made the show did they decide to change that? It doesn't seem very fair.