Toward the end of Genesis, de-evolved Worf is pounding on a door, trying to get to Deanna Troi. Data and Picard are also behind the door. Picard then decides to take Deanna's pheromones with him in a hypospray, in order to lure Worf away. This action obviously put Picard at great risk.
Why didn't Data simply open the doors to the sickbay, and then subdue Worf? Worf was likely stronger but still unquestionably not a match for Data, weapon or not.
(And yes, I know the out-of-universe reason is so that there'd be plenty of action for fans to watch, with Patrick Stewart being pursued by an angry Michael Dorn. But I don't need the obvious real-world explanation.)