A number of people, heroes, civilians, and villains know of Matt's identity and that he is blind. Of specific note, Kingpin, Crossbones, and Typhoid Mary all know.
Some villains, such as Mysterio, have intentionally exploited his senses per Wikipedia:
Since Daredevil's means of sight is based on what his radar sense and enhanced senses are able to detect, if anybody or anything around him does not exhibit any of these factors, then Daredevil would be unable to sense it. In one instance the hallucinogenic drug that Mysterio created was designed with no taste or smell so Daredevil could not tell he was drugged until he consulted Doctor Strange who was able to discover it from the small cross that Mysterio gave to Daredevil in disguise which contained the drug and Strange magically cured him
I've seen, and found instances of times where Daredevil has been affected by noise attacks (explosions, crashes, etc), which confuse or weaken him, but I can't find any evidence of a time where villains specifically set out with a plan to do so.
More specific to the MCU, while the mask may look like wool (I don't entirely agree, but that's neither here nor there), the real material is cotton. This interview with the costume designer explains:
We had to come up with ways to create this mask so that it wasn’t dangerous for him to wear it, but it looked like what we needed it to look like. That was really tricky. It’s made out of a cotton mesh. Layers and layers of it. It has to really conform to his head, but at the same time, he had to be able to see through it. It also had to, in Joe Quesada’s words, 'look really badass.'
There is no reason to believe that the in-universe costume would not be made out of cotton, the same as the out-of-universe costume.