Is there a downside to the serum? It seems pretty much perfect.

  • 3
    have you seen the movie?
    – Himarm
    Apr 22, 2015 at 13:41
  • @Himarm Uh....nope. Is that important? :D
    – LCIII
    Apr 22, 2015 at 13:42
  • yes>.> lol essentially they cant make it anymore and dont have any left.
    – Himarm
    Apr 22, 2015 at 13:42
  • @Himarm Hah. I just found that out. I've updated my question to be something totally different.
    – LCIII
    Apr 22, 2015 at 13:45
  • 1
    Please don't fight to create unnecessary tags, comment-made-by-jack-b-nimble Apr 22, 2015 at 14:45

1 Answer 1


When properly implemented, the only appreciable side effect seems to be that a) Captain America can't get drunk or high and b) his longevity means he will likely see almost everyone he loves wither away and die. One could probably argue that his great endurance and strength probably means that Steve spends most of his day feeling like he's not getting enough exercise and that he needs to go out and run a few miles or lift a few tons in much the same way that many athletes feel antsy if they don't get around to their workouts, but it seems like they give him sufficient exercise that that seldom kicks in.

Captain America's exercise plan

Of course, the majority of cases where the Super-Soldier serum has been administered have led to body deformation, insanity, and such. Whether this is due to an imperfect process or the serum only working due to some quirk in Steve's personal build has varied over the years. Notable failures include Isaiah Bradley (brain damaged and rendered sterile), the other members of his team (deformities and rage problems), the Anti-Cap (insanity), Protocide (initially death, later insanity), Steven Burnside (insanity), and The Sentry (batshit insanity).

The Black Super Soldiers including Isaiah Bradley Super-Soldier failures

  • 4
    Cap has dealt with his own body deformation
    – phantom42
    Apr 22, 2015 at 13:58
  • Can you provide some context/explanation for that picture of a bunch of bulky raisin-looking dudes? I'm not sure how it relates to the answer or question.
    – TylerH
    Apr 22, 2015 at 16:01
  • @TylerH: I've labeled the picture. They're the team that worked with Isaiah Bradley. They're the best case for induced deformities I could find.
    – FuzzyBoots
    Apr 22, 2015 at 18:38
  • “he will likely see almost everyone he loves wither away and die” — that would sound great in the classic super-fast medicine advert side-effects disclaimer voice. Jun 4, 2015 at 15:46
  • ^_^ Honestly, Protocide amused me more. "Side effects may include: death, insanity, death then insanity."
    – FuzzyBoots
    Jun 4, 2015 at 15:51

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