This question: Is there anything special about Agent Smith that makes him become a virus? assumes Agent Smith becomes a virus.
But in this monologue from The Matrix, he speaks with extreme disdain for humans because they are virus-like.
Agent Smith: I'd like to share a revelation that I've had during my time here. It came to me when I tried to classify your species and I realized that you're not actually mammals. Every mammal on this planet instinctively develops a natural equilibrium with the surrounding environment but you humans do not. You move to an area and you multiply and multiply until every natural resource is consumed and the only way you can survive is to spread to another area. There is another organism on this planet that follows the same pattern. Do you know what it is? A virus. Human beings are a disease, a cancer of this planet. You're a plague and we are the cure.
How is this justified behavior for him? Is he just hypocritical?