Characters organised by TV show they had main cast billing. Repeats are omitted. Spoilers are unhidden.

Those in bold have never been visually transformed into another species on screen.

Only one example is given to discount people.

Star Trek
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- James T. Kirk - disguised as Romulan in _The Enterprise Incident_
- **Spock**
- **Leonard McCoy**
- **Montgomery Scott**
- **Nyota Uhura**
- **Pavel Chekov**
- **Hikaru Sulu**

Star Trek: The Animated Series
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- **Christine Chapel**

Star Trek: The Next Generation
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- Jean-Luc Picard - disguised as a Romulan in _Unification_
- William Riker - disguised as a Mintakan in _Who Watches The Watchers_
- Geordi La Forge - transformed into Tarchanne in _Identity Crisis_
- Tasha Yar - half-Romulan daughter in _Redemption_
- Worf - de-evolved by a virus in _Genesis_
- Beverly Crusher - transformed into a dog in _True Q_
- Deanna Troi - disguised as a Romulan in _Face of the Enemy_
- Data - disguised as a Romulan in _Unification_
- **Wesley Crusher**

Star Trek: Deep Space Nine
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- Benjamin Sisko - disguised as a Klingon in _Apocalypse Rising_
- Odo - almost always when not in the Great Link
- Jadzia Dax - disguised as a human in _Trials_and_Tribble-ations_
- **Jake Sisko**
- Miles O'Brien - disguised as a Klingon in _Apocalypse Rising_
- **Quark**
- **Julian Bashir**
- Kira Nerys - disguised as a Cardassian in _Second Skin_
- **Ezri Dax**

Star Trek: Voyager
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- Kathryn Janeway - transformed repeatedly in _Threshold_
- Chakotay - disguised as a Vidiian in _Faces_
- B'Elanna Torres - assimilated by the Borg in _Unimatrix Zero_
- Tom Paris - transformed repeatedly in _Threshold_
- Kes - transforms into an energy being in _The Gift_
- Neelix - disguised as Ferengi in _False Profits_
- The Doctor - takes the appearance of Seven of Nine in _Body and Soul_
- Tuvok - assimilated by the Borg in _Unimatrix Zero_
- Seven of Nine - Borg implants removed until almost human in _The Gift_
- Harry Kim - Infected by Species 8472 in _Scorpion_

Star Trek: Enterprise
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- Jonathan Archer - transformed into a Loque'eque in _Extinction_
- **T'Pol**
- **Phlox**
- Malcolm Reed - disguised as a Suliban in _Detained_
- **Travis Mayweather**
- Hoshi Sato - transformed into a Loque'eque in _Extinction_
- **Charles "Trip" Tucker III**

Star Trek: Discovery
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- **Michael Burnham**
- **Saru**
- Voq - disguised as a human for most appearances
- **Paul Stamets**
- **Sylvia Tilly**
- **Gabriel Lorca**
- **Hugh Culber**
- **Christopher Pike**
- **Nhan**
- **Cleveland "Book" Booker**
- **Jett Reno**
- **Adira Tal**

Star Trek: Picard
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- Agnes Jurati - assimilated by the Borg in _Fly Me to the Moon_
- **Kore Soong (and androids)**
- **Narek**
- **Raffi Musiker**
- **Chris Rios**
- **Elnor**
- **Laris**
- **Tallinn**
- **Adam Soong**

Star Trek: Lower Decks
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- **Beckett Mariner**
- **Brad Boimler**
- **D'Vana Tendi**
- **Sam Rutherford**
- **Carol Freeman**
- Jack Ransom - transformed into a giant head in _Strange Energies_
- **Shaxs**
- **T'Ana**

Star Trek: Strange New Worlds
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- **La'an Noonien-Singh**
- **Erica Ortegas**
- **Joseph M'Benga**
- **Hemmer**
- **Una Chin-Riley**