Interstellar shows us that the main sources of food on Earth are being slowly wiped out by a disease they called The Blight. The solutions they try to enact are 1. to grow more food to make up for what's lost and 2. to leave Earth. But why not just cure The Blight? If it's uncurable (even though they have decades to work on it) it's a big enough problem that you could justify using techniques like Hydroponics/Aeroponics, isolating the crops from others, or GM, modifying them to make them resistant to it.

Did I miss something saying why these techniques wouldn't work?