Dan commentated how the struggle was so crazy, in fact, that animators had the cityscape lights read (in binary code) "F*** you, broadcast standards" in one episode.
"Broadcast Standards and Practices", ReBoot Wikia
Impossible to say, because the show contradicts itself.
Most of the show's references to the physical world's time units suggest that characters in Mainframe experience existence more rapidly than people in the physical world.
This is at odds with Enzo Matrix's aging in season 3, and in particular with Turbo's statement in "The Episode With No Name" (...