Marvel site doesn't list siblings amongst his known relatives, but there is a disclaimer that this is crowdsourced information and not from their own editors. https://www.marvel.com/characters/iceman
William Robert Drake (father), Madeline Beatrice Bass Drake (mother), Mary (cousin), Joel (cousin), Anne (aunt)
Actually, Spider-Man has a history of teaming up with other heroes. Though not officially canon, the "Spider Friends" have had several adventures together, and his friendship with both Ice Man and Fire Star was shown to be deep even beyond their college years. (Angelica even helped him while she was a New Warrior in the 1993 Maximum Carnage arc.) He's worked ...