Not with a hypospray, but with a strong blow to the head, or a sufficiently powerful phaser blast. Could Odo, Laas, or the Female Changeling, etc., be knocked unconscious?
2 Answers
Odo gets knocked out a couple of time, firstly (As @KyleJones has pointed out) in DS9: Vortex by what appears to be a blow to the shoulder. At this point he's in changeling form.
But as they pass through the tunnel, there's a direct hit and rocks come sliding down on top of Odo...
CRODEN : Odo!
He leans down and examines Odo, who is unconscious...
It's not especially clear what caused his injury but from reading the script, it seems likely that the writer originally intended there to be a lot more rocks!
He also gets punched out (by O'Brien) in DS9 : The Assignment but this is whilst in human (non-changeling) form
As regards phasers, there doesn't seem to be a setting that causes unconsciousness in changelings. In DS9 : Homefront we see them testing a "phaser sweep" that they think will force a concealed shapeshifter back into their liquid form and may prevent them from escaping.
BENTEEN : Three point one. If we set the phasers at three point four, we should be able to stun any Changeling we hit and force them back into a gelatinous state.
ODO : I would make it three point five just to be on the safe side. But if you want to do more testing, you'll have to find another guinea pig. I've been shot quite enough for one day.
At higher phaser settings, changelings simply explode
Odo was knocked unconscious by a falling rock in the Star Trek: Deep Space Nine episode "Vortex".
answered Sep 13, 2014 at 2:51
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1Good point. I'd be tempted to call this Early Installment Weirdness though, as later on in episodes like The Ship, it's established that no amount of physical damage can harm shapeshifters. Commented Sep 13, 2014 at 3:22
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But the cellular materials which comprise them, though flexible are likely to be able to withstand a certain amount of force before needing to rest or "reset". It should be theoretically possible to isolate something chemical and/or using variable phaser frequencies to temporarily stun them. Probably would require research to find the proper technology. But they are alive, they are created with cellular material so in theory, there should be something that can cause them to be temporarily insensate. Commented Sep 13, 2014 at 8:16
“What if ______ happened?”questions from the What types of questions should I avoid asking?. Although the question does not sound open ended, unless there is canon about it, it is open-ended. Logic only works so well here. Odo doesn't actually have a head.