Jason Baker beat me to a complete list, so there's no point in finishing this one!
Here we go...
- Tetris blocks
- Green Lantern Power Ring
- The One Ring (should have got this one...thanks @N_Soong)
- Pokémon sphere
- Batarang (from Batman media)
- Cricket gun (from Men in Black)
- Turtle shell (Mario Bros.)
- Golden gun (from Man with the Golden Gun)
- Phaser (Star Trek: TOS)
- ..
- James Bond's Walther PPK
- Dagger from Prince of Persia
- .. Machete from Machete
- Freddy KruegerKrueger's glove (Nightmare on Elm Street)
- Infinity Gauntlet (Marvel Comics)
- ..
- Whip from Indiana Jones series
- ..
- Lara Croft's weapons of choice
- ..
- Donkey Kong mallot
- ..
- Thor's hammer Mjolnir
- Hal'sHAL-9000's eye (thankspossibly, according to @WadCheber)
- .. One of the primary Halo weapons
- Anton Chigurh's pressurized air weapon from No Country for Old Men
- Ninja Turtles' weapons
- ..
- ..
- Light sabers (light and dark side)
- Casey Jones' cricket bat (from Teenage Mutant Ninja Turtles)
- ..
- ..
- Captain America's shield
- Buster sword (from Final Fantasy)
- He-Man's sword
- Lion-O's sword (Thundercats)
- Excalibur
- Portal gun
- Master sword (from Legend of Zelda)
- ..
- Ghostbusters' proton pack