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In Paul's duel with Feyd-Rautha, he is worried when Feyd-Rautha attempts to cheat with a hidden poison needle. But isn't Paul immune to poison? Furthermore, why didn't the snoopers detect the poison?

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    he most likely would have been immune to dieing from the poison though it may have been slowed down considerably by it for a brief period.
    – Himarm
    Commented May 15, 2015 at 18:07
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    If it slowed him down in combat - he dies by a blade. Commented May 15, 2015 at 18:10

1 Answer 1

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The snoopers seem to have missed the poison on the blade because it wasn't deadly (the snoopers are evidently only looking for fatal poisons):

He realigned his own metabolism to match this threat and change the molecules of the soporific, but he felt a thrill of doubt. They’d been prepared with soporific on a blade. A soporific. Nothing to alert a poison snooper, but strong enough to slow the muscles it touched. His enemies had their own plans within plans, their own stacked treacheries.

He's then worried about the dart, not because the poison might kill him but because if they've already used one novel poison against him (albeit ineffectively), the next one may have more of an effect.

Set against the backdrop of a knife fight where every split-second counts, you can see why he'd want to avoid being drugged even if he's reasonably confident of being able to overcome its effects:

“You see it there on my hip?” Feyd-Rautha whispered. “Your death, fool.” And he began twisting himself around, forcing the poisoned needle closer and closer. “It’ll stop your muscles and my knife will finish you. There’ll be never a trace left to detect!”

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    "I will kill you!"—Sting.
    – Lexible
    Commented May 15, 2015 at 18:27
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    "I will bend like a reed in the wind." - Paul Muad'Dib
    – Ghanima
    Commented May 15, 2015 at 20:27
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    “I will always love you.” — Dolly Parton Commented May 15, 2015 at 20:56
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    "You are such a smeghead."
    – Mr Lister
    Commented May 16, 2015 at 11:44
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    You're the smeghead @MrLister! Commented May 18, 2015 at 19:21

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