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I remember a movie from when I was a kid about a science lab in the desert and it really creeped me out. Being older, I'd love to re-watch it and see, probably, how corny it is.

There's been no contact from the desert lab so a recovery team is sent in. The recovery team comes in and they hear or see someone in the ventilation ducts. I believe one of the researchers or a person was experimented on and he killed everyone.

I remember the ending where the survivors are flying away in a small plane and the guy/ mutant is on the wing of the plane.

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Could this be Mind Ripper from 1995?

Set in a remote desert location, government scientists perform reanimation experiments in an underground nuclear facility. The goal is to create a superhuman. Their first subject, "Thor", is a specimen from a suicide found in the desert. In the attempts to bring Thor back, an uncontrollable creature is unleashed. The next morning, a scientist named Alex calls Stockton, one of the overseers of the project, at his home and after an argument, Stockton eventually decides to visit the facility by plane. His son Scott, his daughter Wendy, and Wendy's boyfriend Mark join him.

The film ends with the titular character hanging off of the plane trying to kill the occupants.

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    I agree that this might be the answer. RiffTrax (a successor to Mystery Science Theater 3000) has done this movie. You can see a short clip of it here: rifftrax.com/mind-ripper
    – LAK
    Commented Jun 4, 2018 at 23:13
  • That could be it. I am going to try to watch it tonight and I will let you know. Looks corny lol. Thank you!
    – E. Johnson
    Commented Jun 5, 2018 at 1:16
  • @E.Johnson - And was it the right answer?
    – Valorum
    Commented Sep 17, 2018 at 16:36

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