Could Superman be killed by a bullet made out of Kryptonite?

Question

Superman's only weaknesses are magic and Kryptonite (the latter makes him lose his durability).

If he was shot using a bullet made out of Kryptonite, would it kill him?

Answer 1

From the Smallville Wikia:

A green kryptonite bullet can neutralize both a Kryptonian's invulnerability and their healing factor. This makes bullets a potent weapon against Kryptonians; if a green kryptonite bullet is not removed soon after a Kryptonian is shot, it can potentially kill him or her.

And on wikipedia:

In Lois and Clark, a green Kryptonite bullet is also used to bring Superman back in control when his powers become over-amped by red Kryptonite and a sample of Kryptonite was used to starve out a Kryptonian virus Superman was introduced to by Mrs. Church.

And again:

Green Kryptonite appears in the direct to video movie, Justice League: Doom. In the film, Metallo nearly kills Superman by shooting him the chest with a bullet made of Green Kryptonite, sending him falling from the roof of the Daily Planet and onto the pavement below. Superman's Kryptonian skin prevents the paramedics at the scene from removing the bullet, but he is ultimately saved after Cyborg uses a makeshift Kryptonite laser to cut an incision in the hero's chest, allowing Martian Manhunter to remove the Kryptonite before it kills him.

I'm sure there are other instances of kryptonite bullets, but mostly it's just a handy way of getting the krpytonite to him. Frankly though, superman is unlikely to be killed off so we won't see a kryptonite bullet used successfully on him.

The fact it's in bullet form has nothing, or at least very little to do with the delivery method. Other types of kryptonite would behave the same. I think only green has been made into bullets.