40 years or so ago, I read a paperback that was already old then in which one of the stories had a young adult male protagonist working in a nursing home or hospital.
By coincidence, one of the patients is his uncle. The uncle just lays there doing almost nothing. In the beginning, the uncle occasionally mentions names of companies without saying anything else, and the protagonist notices that if one were to invest in the companies he would make a profit. He starts doing this and mentions to a co-worker that his stock picks come from an "unimpeachable source", which is literally true because the uncle is mentally incompetent. Then the uncle starts naming stars and dates, and the protagonist observes that the stars go nova on the given date. Then the uncle says "Sol" and gives a date in the near future.
The story ends with the protagonist refusing to cooperate with whatever scheme the uncle would have for transcending the impending destruction of Earth and instead taking a vacation so he can enjoy his remaining days. He takes his girlfriend or wife, who doesn't understand the abrupt desire to go on a vacation. There is conflict and it is unpleasant and then the story ends with the protagonist trying to relax on a beach as he expects the Sun to explode and kill everybody.
Another cute event that happens sometime in the story is that the protagonist sends his uncle's bowel movements to be analyzed by a lab every day for some period of time. It comes back with exactly the same weight every day. I read this as saying that the weights actually were the same, but perhaps the intended interpretation was that the lab was refusing to do these redundant analyses and simply giving back the same data repeatedly after the first day.
I remember the title as "Trisomy 21", but I have not been able to find it with that title. "Trisomy 21" is a name for Down's syndrome, and I don't think any of the characters had Down's syndrome.
I'm wanting to reread it because now I realize that it might have been about the protagonist being delusional.
I seem to recall it was in a paperback book that had one or two stories in the book, so maybe it was novella, or maybe a novel. Many of the books from the pile were typical novel length and had two novellas in them with two front covers and no back covers. You could look at one front cover and read one novella, then you could turn it over and look at the other front cover and read the other novella. If you got to the end of one novella and kept flipping pages you'd start seeing the pages of the other novella printed upside down and in reverse order. Ace doubles are about the right era and were popular, so it could have been in one of those. This novella might have been part of one of these two-novella books, or it might have been longer and in a book by itself.
Can anyone here identify the author and correct name of the novella?