For some reason, I remember this book being called, "Leviathan", but I can't seem to find any reference anywhere.
The protagonist, Larry Deaver, is injured and placed into suspended animation.
He is awoken several centuries later to find a sterile planet, populated by modified humans with no thumbs who live in underground cities.
He escapes to the outside, where he meets up with "wild" humans and a submarine that had returned after a failed star-seeding mission and began to re-seed the earth and its oceans with unmodified life.
At one point, a clone of Larry himself is made to hunt down and destroy the natural humans.
I'd like to identify the author and book. I read this sometime in the 70s.