I am pretty sure I watched an anime series episode (or an anime movie) with human heroes that were using laser guns against enemies that were alien creatures or robots with white masks. The masks were similar to the mask in the Iria anime, I think.
If I remember correctly, the laser beams fired from the pistols by the protagonists were able to merge into one super beam. It must have been in the 80s or 90s. I cannot identify it.