I've identified the Messiah complex as the latest X-Men Comic book arc that I'm familiar with, and I'd like to know the major points that have changed X-men/marvel history since then (with the aim of buying the TPBs to fill the gaps in my knowledge). Wikipedia have a listing of all of the preceding story lines since Messia Complex:
"Divided We Stand"
"Manifest Destiny"
"X-Infernus"
"Messiah War"
"Utopia"
"Nation X"
"Necrosha"
"Second Coming"
"Curse of the Mutants"
"Age of X"
"Schism"
"Regenesis"
But I can't tell from these entries which of these has featured the largest change in the world of Marvel.
Now I know this might come down to being subjective, but my main interest in this question is the relevance of the story arc, which one story since the Messia Complex, has had the most impact on the X-men/Marvel still felt "today"?