I watched this film about 2000-2005.
This is a Hong Kong film. I only remember the last scene, a fight where three girls fight with a skeletal creature. He gets a bone plug in the flesh of one of the women and controls her actions. She attacks the other two and takes some hits. In the end, all three are alive.
What I remember but am not sure of: 1 of the 3 females was originally a member of the organization of which the "skeleton-like creature" is the boss. She loves a scientist who is captured then she turns to the good side. Then she tricks her boss and bombs him, maybe revealing his true nature?
I am sure this is not a horror film.