This was a novel I read around 2011 in spurts while visiting my girlfriend who worked in a bookstore. It was in the "Christian novel" section and had the following plot:
Astronauts return from their trip to Mars and Houston is enveloped by a
hurricane bright light, cutting off radio communications. When they finally exit their ship after landing, they're the only people around and walk around empty suburbs.
I'm fairly certain the captain/protagonist was a woman, and she routinely had flashbacks to falling into some sort of tunnel while on Mars.
Note, this definitely isn't The Return as seen in this answer: Novel about astronauts returning to depopulated Earth