Think about suddenly accelerating in a car or an airplane. You're pressed back against the seat, right? Now imagine you put the car in reverse and accelerate. You're still being pushed "backwards" (against the direction of acceleration), but because the vehicle is facing the other way, instead of being pushed into your seat, you'd be pushed away from it.
Now imagine you accelerate while driving forward, spin the car 180, and then accelerate in the opposite direction from before. Both times, you'd be pressed against the seat. You wouldn't be thrown against the windshield, like you would if you'd put the car in reverse instead of spinning it.
The way ships work in The Expanse is to have a big engine at one end of a ship. Because of :handwavy future technology:, they're able to pretty much indefinitely accelerate. That means that to get where they're going, they can accelerate (relative to their destination) to the halfway point, which gives them artificial gravity in the opposite direction of the thrust. (I.e., the ship feels like a tower, with the engine in the basement and the top floor in the nose.) At the halfway point, they stop accelerating and rotate the ship 180; they're still moving in the same direction because they have (a lot of) inertia, but because they're not thrusting, there's no perceived gravity. Then, with the engine pointed at their destination, they start accelerating again, which means they're decelerating relative to the destination while accelerating away from it. This again gives them artificial gravity in the opposite direction of their actual acceleration.
It doesn't matter which way they're traveling, just which way they're accelerating. So by having engines only on one end of the ship, and building the ship like a tower with that engine at the "bottom," they have "gravity" anytime they're under thrust, and the floor will always be the floor and the ceiling will always be the ceiling, because that thrust will always be in the same direction, regardless of which way the ship is traveling. So they build up a bunch of speed going towards their destination, and then slow down in the second half of the trip by accelerating in the opposite direction, which gradually sheds the speed they'd built up in the first half.